High-Density Recombinant Adeno-Associated Viral Particles are Competent Vectors for In Vivo Transduction

Recombinant adeno-associated viral (rAAV) vectors have recently achieved clinical successes in human gene therapy. However, the commonly observed, heavier particles found in rAAV preparations have traditionally been ignored due to their reported low in vitro transduction efficiency. In this study, t...

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Enregistré dans:
Détails bibliographiques
Publié dans:Hum Gene Ther
Auteurs principaux: Wang, Qizhao, Firrman, Jenni, Wu, Zhongren, Pokiniewski, Katie A., Valencia, C. Alexander, Wang, Hairong, Wei, Hongying, Zhuang, Zhenjing, Liu, LinShu, Wunder, Stephanie L., Chin, Mario P.S., Xu, Ruian, Diao, Yong, Dong, Biao, Xiao, Weidong
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2016
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5178025/
https://ncbi.nlm.nih.gov/pubmed/27550145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2016.055
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