Mice with mutant Inf2 show impaired podocyte and slit diaphragm integrity in response to protamine induced kidney injury

Mutations in the INF2 (inverted formin 2) gene, encoding a diaphanous formin family protein that regulates actin cytoskeleton dynamics, cause human focal segmental glomerulosclerosis (FSGS). INF2 interacts directly with certain other mammalian diaphanous formin proteins (mDia) that function as RhoA...

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Publicado en:Kidney Int
Autores principales: Subramanian, Balajikarthick, Sun, Hua, Yan, Paul, Charoonratana, Victoria T., Higgs, Henry N., Wang, Fang, Lai, Ka-Man V., Valenzuela, David M., Brown, Elizabeth J., Schlöndorff, Johannes S., Pollak, Martin R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363079/
https://ncbi.nlm.nih.gov/pubmed/27350175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2016.04.020
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