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Dysregulated Dynein-Mediated Trafficking of Nephrin Causes INF2-related Podocytopathy
BACKGROUND: FSGS caused by mutations in INF2 is characterized by a podocytopathy with mistrafficked nephrin, an essential component of the slit diaphragm. Because INF2 is a formin-type actin nucleator, research has focused on its actin-regulating function, providing an important but incomplete insig...
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| Veröffentlicht in: | J Am Soc Nephrol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Nephrology
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8054882/ https://ncbi.nlm.nih.gov/pubmed/33443052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020081109 |
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