PML nuclear bodies contribute to the basal expression of the mTOR inhibitor DDIT4

The promyelocytic leukemia (PML) protein is an essential component of PML nuclear bodies (PML NBs) frequently lost in cancer. PML NBs coordinate chromosomal regions via modification of nuclear proteins that in turn may regulate genes in the vicinity of these bodies. However, few PML NB-associated ge...

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Udgivet i:Sci Rep
Main Authors: Salsman, Jayme, Stathakis, Alex, Parker, Ellen, Chung, Dudley, Anthes, Livia E., Koskowich, Kara L., Lahsaee, Sara, Gaston, Daniel, Kukurba, Kimberly R., Smith, Kevin S., Chute, Ian C., Léger, Daniel, Frost, Laura D., Montgomery, Stephen B., Lewis, Stephen M., Eskiw, Christopher, Dellaire, Graham
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362932/
https://ncbi.nlm.nih.gov/pubmed/28332630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45038
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