Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres

The promyelocytic leukemia protein (PML) is expressed in most normal human tissues and forms nuclear bodies (NBs) that have roles in gene regulation and cellular processes such as DNA repair, cell cycle control, and cell fate decisions. Using murine C2C12 myoblasts, we demonstrate that activation of...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Autores principales: Salsman, Jayme, Rapkin, Lindsy M, Margam, Nandini N, Duncan, Roy, Bazett-Jones, David P, Dellaire, Graham
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386546/
https://ncbi.nlm.nih.gov/pubmed/28358373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.151
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