Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres

The promyelocytic leukemia protein (PML) is expressed in most normal human tissues and forms nuclear bodies (NBs) that have roles in gene regulation and cellular processes such as DNA repair, cell cycle control, and cell fate decisions. Using murine C2C12 myoblasts, we demonstrate that activation of...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Salsman, Jayme, Rapkin, Lindsy M, Margam, Nandini N, Duncan, Roy, Bazett-Jones, David P, Dellaire, Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386546/
https://ncbi.nlm.nih.gov/pubmed/28358373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.151
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