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Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres

The promyelocytic leukemia protein (PML) is expressed in most normal human tissues and forms nuclear bodies (NBs) that have roles in gene regulation and cellular processes such as DNA repair, cell cycle control, and cell fate decisions. Using murine C2C12 myoblasts, we demonstrate that activation of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Salsman, Jayme, Rapkin, Lindsy M, Margam, Nandini N, Duncan, Roy, Bazett-Jones, David P, Dellaire, Graham
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386546/
https://ncbi.nlm.nih.gov/pubmed/28358373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.151
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