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Inhibition of neddylation induces mitotic defects and alters MKLP1 accumulation at the midbody during cytokinesis
The cullin-RING E3 ubiquitin ligases (CRLs) play crucial roles in modulating the stability of proteins in the cell and are, in turn, regulated by post-translational modification by the ubiquitin-like (Ubl) protein NEDD8. This process, termed neddylation, is reversible through the action of the COP9...
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| Publicado no: | Cell Cycle |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6592236/ https://ncbi.nlm.nih.gov/pubmed/31057046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2019.1612696 |
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