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Regulation of hepatic pyruvate dehydrogenase phosphorylation in offspring glucose intolerance induced by intrauterine hyperglycemia

AIM: Gestational diabetes mellitus (GDM) has been shown to be associated with a high risk of diabetes in offspring. In mitochondria, the inhibition of pyruvate dehydrogenase (PDH) activity by PDH phosphorylation is involved in the development of diabetes. We aimed to determine the role of PDH phosph...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Zhang, Yong, Zhang, Ying, Ding, Guo-Lian, Liu, Xin-Mei, Ye, Jianping, Sheng, Jian-Zhong, Fan, Jianxia, Huang, He-Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362479/
https://ncbi.nlm.nih.gov/pubmed/28148899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14837
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