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Transgenerational Glucose Intolerance of Tumor Necrosis Factor with Epigenetic Alteration in Rat Perirenal Adipose Tissue Induced by Intrauterine Hyperglycemia

Changes in DNA methylation may play a role in the genetic mechanism underlying glucose intolerance in the offspring of mothers with diabetes. Here, we established a rat model of moderate intrauterine hyperglycemia induced by streptozotocin to detect glucose and lipid metabolism of first-generation (...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Su, Rina, Yan, Jie, Yang, Huixia
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735892/
https://ncbi.nlm.nih.gov/pubmed/26881249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4952801
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