Regulation of hepatic pyruvate dehydrogenase phosphorylation in offspring glucose intolerance induced by intrauterine hyperglycemia

AIM: Gestational diabetes mellitus (GDM) has been shown to be associated with a high risk of diabetes in offspring. In mitochondria, the inhibition of pyruvate dehydrogenase (PDH) activity by PDH phosphorylation is involved in the development of diabetes. We aimed to determine the role of PDH phosph...

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Udgivet i:Oncotarget
Main Authors: Zhang, Yong, Zhang, Ying, Ding, Guo-Lian, Liu, Xin-Mei, Ye, Jianping, Sheng, Jian-Zhong, Fan, Jianxia, Huang, He-Feng
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362479/
https://ncbi.nlm.nih.gov/pubmed/28148899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14837
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