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Regulation of hepatic pyruvate dehydrogenase phosphorylation in offspring glucose intolerance induced by intrauterine hyperglycemia

AIM: Gestational diabetes mellitus (GDM) has been shown to be associated with a high risk of diabetes in offspring. In mitochondria, the inhibition of pyruvate dehydrogenase (PDH) activity by PDH phosphorylation is involved in the development of diabetes. We aimed to determine the role of PDH phosph...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Yong, Zhang, Ying, Ding, Guo-Lian, Liu, Xin-Mei, Ye, Jianping, Sheng, Jian-Zhong, Fan, Jianxia, Huang, He-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362479/
https://ncbi.nlm.nih.gov/pubmed/28148899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14837
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