Transgenerational Glucose Intolerance With Igf2/H19 Epigenetic Alterations in Mouse Islet Induced by Intrauterine Hyperglycemia

Gestational diabetes mellitus (GDM) has been shown to be associated with high risk of diabetes in offspring. However, the mechanisms involved and the possibilities of transgenerational transmission are still unclear. We intercrossed male and female adult control and first-generation offspring of GDM...

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Autors principals: Ding, Guo-Lian, Wang, Fang-Fang, Shu, Jing, Tian, Shen, Jiang, Ying, Zhang, Dan, Wang, Ning, Luo, Qiong, Zhang, Yu, Jin, Fan, Leung, Peter C.K., Sheng, Jian-Zhong, Huang, He-Feng
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
Matèries:
Islet Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331740/
https://ncbi.nlm.nih.gov/pubmed/22447856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1314
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