Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways

Recent evidence indicates that protein kinase CK1α may support the growth of multiple myeloma (MM) plasma cells. Here, by analyzing a large cohort of MM cases, we found that high CK1α mRNA levels are virtually associated with all MM patients. Moreover, we provided functional evidence that CK1α activ...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Oncotarget
Κύριοι συγγραφείς: Manni, Sabrina, Carrino, Marilena, Manzoni, Martina, Gianesin, Ketty, Nunes, Sara Canovas, Costacurta, Matteo, Tubi, Laura Quotti, Macaccaro, Paolo, Taiana, Elisa, Cabrelle, Anna, Barilà, Gregorio, Martines, Annalisa, Zambello, Renato, Bonaldi, Laura, Trentin, Livio, Neri, Antonino, Semenzato, Gianpietro, Piazza, Francesco
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Impact Journals LLC 2017
Θέματα:
Research Paper
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362429/
https://ncbi.nlm.nih.gov/pubmed/28099937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14654
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