Inactivation of CK1α in multiple myeloma empowers drug cytotoxicity by affecting AKT and β-catenin survival signaling pathways

Recent evidence indicates that protein kinase CK1α may support the growth of multiple myeloma (MM) plasma cells. Here, by analyzing a large cohort of MM cases, we found that high CK1α mRNA levels are virtually associated with all MM patients. Moreover, we provided functional evidence that CK1α activ...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Manni, Sabrina, Carrino, Marilena, Manzoni, Martina, Gianesin, Ketty, Nunes, Sara Canovas, Costacurta, Matteo, Tubi, Laura Quotti, Macaccaro, Paolo, Taiana, Elisa, Cabrelle, Anna, Barilà, Gregorio, Martines, Annalisa, Zambello, Renato, Bonaldi, Laura, Trentin, Livio, Neri, Antonino, Semenzato, Gianpietro, Piazza, Francesco
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362429/
https://ncbi.nlm.nih.gov/pubmed/28099937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14654
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker