Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell death

BACKGROUND: Glycogen Synthase Kinase-3 (GSK-3) α and β are two serine-threonine kinases controlling insulin, Wnt/β-catenin, NF-κB signaling and other cancer-associated transduction pathways. Recent evidence suggests that GSK-3 could function as growth-promoting kinases, especially in malignant cells...

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Autori principali: Piazza, Francesco, Manni, Sabrina, Tubi, Laura Quotti, Montini, Barbara, Pavan, Laura, Colpo, Anna, Gnoato, Marianna, Cabrelle, Anna, Adami, Fausto, Zambello, Renato, Trentin, Livio, Gurrieri, Carmela, Semenzato, Gianpietro
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958942/
https://ncbi.nlm.nih.gov/pubmed/20920357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-526
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