Inhibition of protein kinase CK2 with the clinical-grade small ATP-competitive compound CX-4945 or by RNA interference unveils its role in acute myeloid leukemia cell survival, p53-dependent apoptosis and daunorubicin-induced cytotoxicity

BACKGROUND: The involvement of protein kinase CK2 in sustaining cancer cell survival could have implications also in the resistance to conventional and unconventional therapies. Moreover, CK2 role in blood tumors is rapidly emerging and this kinase has been recognized as a potential therapeutic targ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Quotti Tubi, Laura, Gurrieri, Carmela, Brancalion, Alessandra, Bonaldi, Laura, Bertorelle, Roberta, Manni, Sabrina, Pavan, Laura, Lessi, Federica, Zambello, Renato, Trentin, Livio, Adami, Fausto, Ruzzene, Maria, Pinna, Lorenzo A, Semenzato, Gianpietro, Piazza, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852751/
https://ncbi.nlm.nih.gov/pubmed/24283803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-78
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados