Inhibition of protein kinase CK2 with the clinical-grade small ATP-competitive compound CX-4945 or by RNA interference unveils its role in acute myeloid leukemia cell survival, p53-dependent apoptosis and daunorubicin-induced cytotoxicity

BACKGROUND: The involvement of protein kinase CK2 in sustaining cancer cell survival could have implications also in the resistance to conventional and unconventional therapies. Moreover, CK2 role in blood tumors is rapidly emerging and this kinase has been recognized as a potential therapeutic targ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Quotti Tubi, Laura, Gurrieri, Carmela, Brancalion, Alessandra, Bonaldi, Laura, Bertorelle, Roberta, Manni, Sabrina, Pavan, Laura, Lessi, Federica, Zambello, Renato, Trentin, Livio, Adami, Fausto, Ruzzene, Maria, Pinna, Lorenzo A, Semenzato, Gianpietro, Piazza, Francesco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2013
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852751/
https://ncbi.nlm.nih.gov/pubmed/24283803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-6-78
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak