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Antivascular and antitumor properties of the tubulin-binding chalcone TUB091
We investigated the microtubule-destabilizing, vascular-targeting, anti-tumor and anti-metastatic activities of a new series of chalcones, whose prototype compound is (E)-3-(3’’-amino-4’’-methoxyphenyl)-1-(5’-methoxy-3’,4’-methylendioxyphenyl)-2-methylprop-2-en-1-one (TUB091). X-ray crystallography...
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| Udgivet i: | Oncotarget |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Impact Journals LLC
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362409/ https://ncbi.nlm.nih.gov/pubmed/27224920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9527 |
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