Caricamento...
A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF) and Liver Receptor Homolog-1 (LRH-1)
Oct4 is a transcription factor required for maintaining pluripotency and self-renewal in stem cells. Prior to differentiation, Oct4 must be silenced to allow for the development of the three germ layers in the developing embryo. This fine-tuning is controlled by the nuclear receptors, liver receptor...
Salvato in:
Pubblicato in: | J Mol Biol |
---|---|
Autori principali: | , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2016
|
Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362318/ https://ncbi.nlm.nih.gov/pubmed/27984042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.10.025 |
Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|