Orphan Nuclear Receptor LRH-1 Is Required To Maintain Oct4 Expression at the Epiblast Stage of Embryonic Development

Oct4 plays an essential role in maintaining the inner cell mass and pluripotence of embryonic stem (ES) cells. The expression of Oct4 is regulated by the proximal enhancer and promoter in the epiblast and by the distal enhancer and promoter at all other stages in the pluripotent cell lineage. Here w...

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Bibliografiska uppgifter
Huvudupphovsmän: Gu, Peili, Goodwin, Bryan, Chung, Arthur C.-K., Xu, Xueping, Wheeler, David A., Price, Roger R., Galardi, Cristin, Peng, Li, Latour, Anne M., Koller, Beverly H., Gossen, Jan, Kliewer, Steven A., Cooney, Austin J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2005
Ämnen:
Gene Expression
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084298/
https://ncbi.nlm.nih.gov/pubmed/15831456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.9.3492-3505.2005
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