Chargement en cours...
A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF) and Liver Receptor Homolog-1 (LRH-1)
Oct4 is a transcription factor required for maintaining pluripotency and self-renewal in stem cells. Prior to differentiation, Oct4 must be silenced to allow for the development of the three germ layers in the developing embryo. This fine-tuning is controlled by the nuclear receptors, liver receptor...
Enregistré dans:
| Publié dans: | J Mol Biol |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5362318/ https://ncbi.nlm.nih.gov/pubmed/27984042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.10.025 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|