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Occlusion of the Ribosome Binding Site Connects the Translational Initiation Frequency, mRNA Stability and Premature Transcription Termination

Protein production is controlled by ribosome binding to the messenger RNA (mRNA), quantified in part by the binding affinity between the ribosome and the ribosome binding sequence on the mRNA. Using the E. coli lac operon as model, Ringquist et al. (1992) found a more than 1,000-fold difference in p...

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Bibliografische gegevens
Gepubliceerd in:Front Microbiol
Hoofdauteurs: Eriksen, Mette, Sneppen, Kim, Pedersen, Steen, Mitarai, Namiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361652/
https://ncbi.nlm.nih.gov/pubmed/28382022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00362
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