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Occlusion of the Ribosome Binding Site Connects the Translational Initiation Frequency, mRNA Stability and Premature Transcription Termination

Protein production is controlled by ribosome binding to the messenger RNA (mRNA), quantified in part by the binding affinity between the ribosome and the ribosome binding sequence on the mRNA. Using the E. coli lac operon as model, Ringquist et al. (1992) found a more than 1,000-fold difference in p...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Eriksen, Mette, Sneppen, Kim, Pedersen, Steen, Mitarai, Namiko
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361652/
https://ncbi.nlm.nih.gov/pubmed/28382022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.00362
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