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The Immunosuppressant Mycophenolic Acid Alters Nucleotide and Lipid Metabolism in an Intestinal Cell Model

The study objective was to elucidate the molecular mechanisms underlying the negative effects of mycophenolic acid (MPA) on human intestinal cells. Effects of MPA exposure and guanosine supplementation on nucleotide concentrations in LS180 cells were assessed using liquid chromatography-mass spectro...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Heischmann, Svenja, Dzieciatkowska, Monika, Hansen, Kirk, Leibfritz, Dieter, Christians, Uwe
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361167/
https://ncbi.nlm.nih.gov/pubmed/28327659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45088
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