A High-Throughput U-HPLC-MS/MS Assay for the Quantification of Mycophenolic Acid and its Major Metabolites Mycophenolic Acid Glucuronide and Mycophenolic Acid Acyl-Glucuronide in Human Plasma and Urine

Mycophenolic acid (MPA) is used as an immunosuppressant after organ transplantation and for the treatment of immune diseases. There is increasing evidence that therapeutic drug monitoring and plasma concentration-guided dose adjustments are beneficial for patients to maintain immunosuppressive effic...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Klepacki, Jacek, Klawitter, Jelena, Bendrick-Peart, Jamie, Schniedewind, Bjoern, Heischmann, Svenja, Shokati, Touraj, Christians, Uwe, Klawitter, Jost
التنسيق: Artigo
اللغة:Inglês
منشور في: 2011
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232328/
https://ncbi.nlm.nih.gov/pubmed/21839692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2011.07.021
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