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Mass Spectrometry-Based Multiplexing for the Analysis of Biomarkers in Drug Development and Clinical Diagnostics- How Much is too Much?

Biomarkers, or more specifically molecular markers, can detect biochemical changes associated with disease processes and drug effects before histopathological and pathophysiological changes occur. Multiplexing technologies such as high-performance liquid chromatography/mass spectrometry (LC-MS) allo...

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Detalhes bibliográficos
Main Authors: Christians, Uwe, Klepacki, Jacek, Shokati, Touraj, Klawitter, Jost, Klawitter, Jelena
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640576/
https://ncbi.nlm.nih.gov/pubmed/23645936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.microc.2012.02.011
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