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The Immunosuppressant Mycophenolic Acid Alters Nucleotide and Lipid Metabolism in an Intestinal Cell Model

The study objective was to elucidate the molecular mechanisms underlying the negative effects of mycophenolic acid (MPA) on human intestinal cells. Effects of MPA exposure and guanosine supplementation on nucleotide concentrations in LS180 cells were assessed using liquid chromatography-mass spectro...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Heischmann, Svenja, Dzieciatkowska, Monika, Hansen, Kirk, Leibfritz, Dieter, Christians, Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5361167/
https://ncbi.nlm.nih.gov/pubmed/28327659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45088
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