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Responses to LPS boost effector CD8 T-cell accumulation outside of signals 1 and 2

Immunization with adjuvant plus antigen induces durable T-cell immunity and is a mainstay of vaccines. Here, the consequence of separating antigen stimulation of T cells from the adjuvant response was studied in a re-transfer model. Effector CD8 T cells in recipient mice were exposed to lipopolysacc...

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Detalhes bibliográficos
Publicado no:Cell Mol Immunol
Main Authors: Liu, Wenhai, Menoret, Antoine, Vella, Anthony T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360877/
https://ncbi.nlm.nih.gov/pubmed/26189366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.69
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