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Targeting Poly I:C to the TLR3-independent pathway boosts effector CD8 T cell differentiation through IFNα/β

Poly I:C is an adjuvant used for anti-tumor treatment and vaccines because of its prominent effects on CD8 T cells and NK cells. Poly I:C binds TLR3 and this interaction is thought to be central for driving cell-mediated immune responses. We investigated the importance of TLR3 in poly I:C-mediated e...

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書誌詳細
主要な著者: Ngoi, Soo M., Tovey, Michael G., Vella, Anthony T.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676428/
https://ncbi.nlm.nih.gov/pubmed/19017955
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