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Targeting Poly I:C to the TLR3-independent pathway boosts effector CD8 T cell differentiation through IFNα/β
Poly I:C is an adjuvant used for anti-tumor treatment and vaccines because of its prominent effects on CD8 T cells and NK cells. Poly I:C binds TLR3 and this interaction is thought to be central for driving cell-mediated immune responses. We investigated the importance of TLR3 in poly I:C-mediated e...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676428/ https://ncbi.nlm.nih.gov/pubmed/19017955 |
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