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African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development

Genetic diversity is greater in Africa than in other continental populations. Genetic variability in genes encoding drug metabolizing enzymes may contribute to the high numbers of adverse drug reactions reported in Africa. We reviewed publications (1995–April 2016) reporting frequencies of known cyt...

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Podrobná bibliografie
Vydáno v:EBioMedicine
Hlavní autoři: Rajman, Iris, Knapp, Laura, Morgan, Thomas, Masimirembwa, Collen
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360579/
https://ncbi.nlm.nih.gov/pubmed/28237373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.02.017
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