African Genetic Diversity: Implications for Cytochrome P450-mediated Drug Metabolism and Drug Development

Genetic diversity is greater in Africa than in other continental populations. Genetic variability in genes encoding drug metabolizing enzymes may contribute to the high numbers of adverse drug reactions reported in Africa. We reviewed publications (1995–April 2016) reporting frequencies of known cyt...

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Bibliografiska uppgifter
I publikationen:EBioMedicine
Huvudupphovsmän: Rajman, Iris, Knapp, Laura, Morgan, Thomas, Masimirembwa, Collen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2017
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360579/
https://ncbi.nlm.nih.gov/pubmed/28237373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.02.017
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