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Inducible T cell kinase regulates the acquisition of cytolytic capacity and degranulation in CD8(+) cytotoxic T lymphocytes()
Patients with mutations in ITK are susceptible to viral infections, particularly Epstein Barr Virus, suggesting that these patients have defective function of CD8(+) cytolytic T lymphocytes (CTLs). Here, we evaluated the effects of ITK-deficiency on cytolysis in murine CTLs deficient in ITK, and bot...
Tallennettuna:
| Julkaisussa: | J Immunol |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5360469/ https://ncbi.nlm.nih.gov/pubmed/28213500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601202 |
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