Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis

Intervertebral disc (IVD) degeneration is the leading cause of disability with no disease-modifying treatment. IVD degeneration is associated with instable mechanical loading in the spine, but little is known about how mechanical stress regulates nucleus notochordal (NC) cells to maintain IVD homeos...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bone Res
Egile Nagusiak: Bian, Qin, Ma, Lei, Jain, Amit, Crane, Janet L, Kebaish, Khaled, Wan, Mei, Zhang, Zhengdong, Edward Guo, X, Sponseller, Paul D, Séguin, Cheryle A, Riley, Lee H, Wang, Yongjun, Cao, Xu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360159/
https://ncbi.nlm.nih.gov/pubmed/28392965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2017.8
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