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Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis
Intervertebral disc (IVD) degeneration is the leading cause of disability with no disease-modifying treatment. IVD degeneration is associated with instable mechanical loading in the spine, but little is known about how mechanical stress regulates nucleus notochordal (NC) cells to maintain IVD homeos...
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| Publicado no: | Bone Res |
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| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5360159/ https://ncbi.nlm.nih.gov/pubmed/28392965 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2017.8 |
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