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Impact of Divalent Metal Ions on Regulation of Adenylyl Cyclase Isoforms by Forskolin Analogs

Mammalian membranous adenylyl cyclases (mACs) play an important role in transmembrane signaling events in almost every cell and represent an interesting drug target. Forskolin (FS) is an invaluable research tool, activating AC isoforms 1-8. However, there is a paucity of AC isoform-selective FS anal...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochem Pharmacol
Main Authors: Erdorf, Miriam, Mou, Tung-Chung, Seifert, Roland
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360100/
https://ncbi.nlm.nih.gov/pubmed/21843517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.07.099
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