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STRUCTURAL BASIS FOR INHIBITION OF MAMMALIAN ADENYLYL CYCLASE BY CALCIUM
Type V and VI mammalian adenylyl cyclases (AC5, AC6) are inhibited by Ca(2+) at both sub- and supra-micromolar concentration. This inhibition may provide feedback in situations where cAMP promotes opening of Ca(2+) channels, allowing fine control of cardiac contraction and rhythmicity in cardiac tis...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680196/ https://ncbi.nlm.nih.gov/pubmed/19243146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi802122k |
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