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Direct demonstration of discrete Ca(2+) microdomains associated with different isoforms of adenylyl cyclase

Ca(2+)-sensitive adenylyl cyclases (ACs) orchestrate dynamic interplay between Ca(2+) and cAMP that is a crucial feature of cellular homeostasis. Significantly, these ACs are highly selective for capacitative Ca(2+) entry (CCE) over other modes of Ca(2+) increase. To directly address the possibility...

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Detalhes bibliográficos
Main Authors: Willoughby, Debbie, Wachten, Sebastian, Masada, Nanako, Cooper, Dermot M. F.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794712/
https://ncbi.nlm.nih.gov/pubmed/20016071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.062067
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