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Characterization of proteoforms with unknown post-translational modifications using the MIScore
Various proteoforms may be generated from a single gene due to primary structure alterations (PSAs) such as genetic variations, alternative splicing, and post-translational modifications (PTMs). Top-down mass spectrometry is capable of analyzing intact proteins and identifying patterns of multiple P...
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Publicado no: | J Proteome Res |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5359983/ https://ncbi.nlm.nih.gov/pubmed/27291504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.5b01098 |
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