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Curcumin Improves Palmitate-Induced Insulin Resistance in Human Umbilical Vein Endothelial Cells by Maintaining Proteostasis in Endoplasmic Reticulum

Dysfunction of proteasome and autophagy will result in disturbance of endoplasmic reticulum (ER) proteostasis, and thus lead to long-term and chronic ER stress and subsequent unfolded protein response (UPR), which is implicated in the occurrence and development of insulin resistance. Curcumin exerts...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Ye, Mao, Qiu, Hong, Cao, Yingkang, Zhang, Min, Mi, Yan, Yu, Jing, Wang, Changhua
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359258/
https://ncbi.nlm.nih.gov/pubmed/28377722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00148
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