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Endoplasmic reticulum proteostasis impairment in aging

Perturbed neuronal proteostasis is a salient feature shared by both aging and protein misfolding disorders. The proteostasis network controls the health of the proteome by integrating pathways involved in protein synthesis, folding, trafficking, secretion, and their degradation. A reduction in the b...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Martínez, Gabriela, Duran‐Aniotz, Claudia, Cabral‐Miranda, Felipe, Vivar, Juan P., Hetz, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5506418/
https://ncbi.nlm.nih.gov/pubmed/28436203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12599
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