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Protein Folding and the Challenges of Maintaining Endoplasmic Reticulum Proteostasis in Idiopathic Pulmonary Fibrosis
Alveolar epithelial type II (AEII) cells are “professional” secretory cells that synthesize and secrete massive quantities of proteins to produce pulmonary surfactant and maintain airway immune defenses. To facilitate this high level of protein synthesis, AEII cells are equipped with an elaborate en...
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| Veröffentlicht in: | Ann Am Thorac Soc |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Thoracic Society
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5711273/ https://ncbi.nlm.nih.gov/pubmed/29161089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201703-207AW |
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