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Protein Folding and the Challenges of Maintaining Endoplasmic Reticulum Proteostasis in Idiopathic Pulmonary Fibrosis

Alveolar epithelial type II (AEII) cells are “professional” secretory cells that synthesize and secrete massive quantities of proteins to produce pulmonary surfactant and maintain airway immune defenses. To facilitate this high level of protein synthesis, AEII cells are equipped with an elaborate en...

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Bibliografski detalji
Izdano u:Ann Am Thorac Soc
Glavni autori: Romero, Freddy, Summer, Ross
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711273/
https://ncbi.nlm.nih.gov/pubmed/29161089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201703-207AW
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