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Protein Folding and the Challenges of Maintaining Endoplasmic Reticulum Proteostasis in Idiopathic Pulmonary Fibrosis

Alveolar epithelial type II (AEII) cells are “professional” secretory cells that synthesize and secrete massive quantities of proteins to produce pulmonary surfactant and maintain airway immune defenses. To facilitate this high level of protein synthesis, AEII cells are equipped with an elaborate en...

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Detalles Bibliográficos
Publicado en:Ann Am Thorac Soc
Main Authors: Romero, Freddy, Summer, Ross
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711273/
https://ncbi.nlm.nih.gov/pubmed/29161089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/AnnalsATS.201703-207AW
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