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The Drosha-DGCR8 complex in primary microRNA processing
RNase III proteins play key roles in microRNA (miRNA) biogenesis. The nuclear RNase III Drosha cleaves primary miRNAs (pri-miRNAs) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic RNase III Dicer to generate mature miRNAs. While Dicer (class III) and other simple RNa...
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| Publicado en: | Genes Dev |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC535913/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15574589/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1262504 |
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