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Tissue Factor-Factor VIIa Complex Triggers Protease Activated Receptor 2-Dependent Growth Factor Release and Migration in Ovarian Cancer

OBJECTIVE: Enhanced tissue factor (TF) expression in epithelial ovarian cancer (EOC) is associated with aggressive disease. Our objective was to evaluate the role of the TF-factor VIIa-protease-activated receptor-2 (PAR-2) pathway in human EOC. METHODS: TCGA RNAseq data from EOC databases were analy...

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Detalhes bibliográficos
Publicado no:Gynecol Oncol
Main Authors: Chanakira, Alice, Westmark, Pamela R., Ong, Irene M., Sheehan, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359044/
https://ncbi.nlm.nih.gov/pubmed/28148395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2017.01.022
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