Iron importers Zip8 and Zip14 are expressed in retina and regulated by retinal iron levels

Intracellular retinal iron accumulation has been implicated in the pathogenesis of age-related macular degeneration (AMD), the leading cause of irreversible blindness among individuals over the age of 50. Ceruloplasmin/hephaestin double knockout mice (Cp/Heph DKO) and hepcidin knockout mice (Hepc KO...

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Bibliographic Details
Published in:Exp Eye Res
Main Authors: Sterling, Jacob, Guttha, Samyuktha, Song, Ying, Song, Delu, Hadziahmetovic, Majda, Dunaief, Joshua L.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5359041/
https://ncbi.nlm.nih.gov/pubmed/28057442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2016.12.008
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