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Retinal iron homeostasis in health and disease

Iron is essential for life, but excess iron can be toxic. As a potent free radical creator, iron generates hydroxyl radicals leading to significant oxidative stress. Since iron is not excreted from the body, it accumulates with age in tissues, including the retina, predisposing to age-related oxidat...

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Bibliographic Details
Main Authors: Song, Delu, Dunaief, Joshua L.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695389/
https://ncbi.nlm.nih.gov/pubmed/23825457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2013.00024
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