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Retinal iron homeostasis in health and disease

Iron is essential for life, but excess iron can be toxic. As a potent free radical creator, iron generates hydroxyl radicals leading to significant oxidative stress. Since iron is not excreted from the body, it accumulates with age in tissues, including the retina, predisposing to age-related oxidat...

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Detalhes bibliográficos
Main Authors: Song, Delu, Dunaief, Joshua L.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695389/
https://ncbi.nlm.nih.gov/pubmed/23825457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2013.00024
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