A High Serum Iron Level Causes Mouse Retinal Iron Accumulation Despite an Intact Blood-Retinal Barrier

The retina can be shielded by the blood-retinal barrier. Because photoreceptors are damaged by excess iron, it is important to understand whether the blood-retinal barrier protects against high serum iron levels. Bone morphogenic protein 6 (Bmp6) knockout mice have serum iron overload. Herein, we te...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Liangliang, Li, Yafeng, Song, Delu, Song, Ying, Theurl, Milan, Wang, Chenguang, Cwanger, Alyssa, Su, Guanfang, Dunaief, Joshua L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2014
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215029/
https://ncbi.nlm.nih.gov/pubmed/25174877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.07.008
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