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CD1 Mouse Retina Is Shielded From Iron Overload Caused by a High Iron Diet
PURPOSE: High RPE iron levels have been associated with age-related macular degeneration. Mutation of the ferroxidase ceruloplasmin leads to RPE iron accumulation and degeneration in patients with aceruloplasminemia; mice lacking ceruloplasmin and its homolog hephaestin have a similar RPE degenerati...
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| Udgivet i: | Invest Ophthalmol Vis Sci |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Association for Research in Vision and Ophthalmology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4539129/ https://ncbi.nlm.nih.gov/pubmed/26275132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-17026 |
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