ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair

Chromatin connects DNA damage response factors to sites of damaged DNA to promote the signaling and repair of DNA lesions. The histone H2A variants H2AX, H2AZ, and macroH2A represent key chromatin constituents that facilitate DNA repair. Through proteomic screening of these variants, we identified Z...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Leung, Justin W.C., Makharashvili, Nodar, Agarwal, Poonam, Chiu, Li-Ya, Pourpre, Renaud, Cammarata, Michael B., Cannon, Joe R., Sherker, Alana, Durocher, Daniel, Brodbelt, Jennifer S., Paull, Tanya T., Miller, Kyle M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358723/
https://ncbi.nlm.nih.gov/pubmed/28242625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.292516.116
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