PP54. NANO-ENCAPSULATED DISULFIRAM TARGETS GLIOBLASTOMA STEM CELLS IN VITRO AND IN VIVO BY MODULATION OF HYPOXIA-NF-KB PATHWAY

BACKGROUND: Despite decades of research the therapeutic outcome of Glioblastoma Multiforme (GBM) remains dismal as no contemporary chemotherapeutic regimen is effective. Recent understanding of the molecular mechanisms behind chemoresistance has focussed on a small population (~1%) of GBM cancer ste...

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Publicado en:Neuro Oncol
Main Authors: Kannappan, Dr Vinodh, Wang, Dr Zhipeng, Liu, Dr Peng, Brown, Dr Sarah, Butcher, Ms Kate, Azar, Mr Karim, Bian, Prof Xiuwu, Armesilla, Dr Angel, Darling, Prof John, Wang, Prof Weiguang
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5358628/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now293.054
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