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Disulfiram targets glioblastoma-stem-like cells in vitro and in vivo
BACKGROUND: Glioblastoma multiform (GBM) is the most aggressive adult primary brain tumour with median survival time less than 12 months. GBM are extensively hypoxygenated tumours. Intra-tumoural hypoxia induces GBM-stem-like-cells (GSCs) are highly locally invasive and resistant to all currently av...
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Publicado no: | Neuro Oncol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5791619/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.089 |
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