Disulfiram targets glioblastoma-stem-like cells in vitro and in vivo

BACKGROUND: Glioblastoma multiform (GBM) is the most aggressive adult primary brain tumour with median survival time less than 12 months. GBM are extensively hypoxygenated tumours. Intra-tumoural hypoxia induces GBM-stem-like-cells (GSCs) are highly locally invasive and resistant to all currently av...

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Bibliografiset tiedot
Julkaisussa:Neuro Oncol
Päätekijät: Azar, Karim, Kannappan, Vinodh, Liu, Ying, Butcher, Kate, Morris, Mark, Armesilla, Angel, Darling, John, Wang, Weiguang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2018
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Abstracts
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791619/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.089
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